Carbamic acid,N-6-quinolinyl-, 2,5-dioxo-1-pyrrolidinyl ester

Carbamic acid,N-6-quinolinyl-, 2,5-dioxo-1-pyrrolidinyl ester - Names and Identifiers

Name	6-Aminoquinolyl-N-hydroxysuccinimidylcarbamate
Synonyms	AQC AccQ.Fluor 2,5-Dioxo-1-pyrrolidinyl 6-Quinolylcarbamate 6-Aminoquinolyl-N-hydroxysuccinimidylcarbamate 2,5-Dioxopyrrolidin-1-yl quinolin-6-ylcarbamate 6-Aminoquinoline-N-hydroxy-succinimidyl carbamate Carbamic acid,N-6-quinolinyl-, 2,5-dioxo-1-pyrrolidinyl ester
CAS	148757-94-2

Carbamic acid,N-6-quinolinyl-, 2,5-dioxo-1-pyrrolidinyl ester - Physico-chemical Properties

Molecular Formula	C14H11N3O4
Molar Mass	285.25
Density	1.48±0.1 g/cm3(Predicted)
Melting Point	>180°C (dec.)
Appearance	Form Solid, color White to Light Yellow
pKa	10.41±0.43(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Stability	Hygroscopic, Moisture Sensitive
Physical and Chemical Properties	Bioactive AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent for fluorescence detection of amino acid or protein sequences by high performance liquid chromatography. AQC reacts with primary and secondary amino acids to produce fluorescent derivatives, allowing the detection of amino acids at picomolar levels.
Use	A useful chemical for amino acid and protein detection.

Carbamic acid,N-6-quinolinyl-, 2,5-dioxo-1-pyrrolidinyl ester - Reference

Reference

1. [IF=5.118] Shan-Shan Zhang et al."Two Novel Multi-Functional Peptides from Meat and Visceral Mass of Marine Snail Neptunea arthritica cumingii and Their Activities In Vitro and In Vivo."Mar Drugs. 2018 Dec;16(12):473

Carbamic acid,N-6-quinolinyl-, 2,5-dioxo-1-pyrrolidinyl ester - In vitro study

The use of AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate), which reacts with primary and secondary amino acids to yield fluorescent derivates (λ excitation and emission at 250 and 395 nm, respectively), allowing amino acid detection at under-picomolar levels, overcomes many of the drawbacks associated with the rest of derivatising reagents.

Last Update：2024-04-09 20:52:54